BDBM710520 US20250002493, Compound I-2-28::US20250002493, Embodiment 42

SMILES [2H]C([2H])([2H])N[C@@H](C)C(=O)N[C@H](C(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccc(F)cc3F)cc21)C(C)(C)C

InChI Key InChIKey=VMJKIHXOXYMIQM-UKDQJQFQSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 710520   

TargetBaculoviral IAP repeat-containing protein 2 [254-364](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710520(US20250002493, Embodiment 42 | US20250002493, Comp...)
Affinity DataKi:  1.90nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710520(US20250002493, Embodiment 42 | US20250002493, Comp...)
Affinity DataKi:  6.70nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [238-358](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710520(US20250002493, Embodiment 42 | US20250002493, Comp...)
Affinity DataKi:  185nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent