BDBM710528 US20250002493, Compound I-3-3::US20250002493, Embodiment 52

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1F)c(=O)n2C)C(C)(C)C

InChI Key InChIKey=GSYCIPSRQKSJPJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 710528   

TargetBaculoviral IAP repeat-containing protein 2 [254-364](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710528(US20250002493, Embodiment 52 | US20250002493, Comp...)
Affinity DataKi:  1.40nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710528(US20250002493, Embodiment 52 | US20250002493, Comp...)
Affinity DataKi:  2.20nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [238-358](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710528(US20250002493, Embodiment 52 | US20250002493, Comp...)
Affinity DataKi:  13.7nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent