BDBM710529 US20250002493, Compound I-3-6::US20250002493, Embodiment 55

SMILES CCn1c2c(cc(Cc3ccc(F)cc3F)c1=O)N(C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)CC2

InChI Key InChIKey=XVRNAIWVXGNREC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 710529   

TargetBaculoviral IAP repeat-containing protein 2 [254-364](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710529(US20250002493, Embodiment 55 | US20250002493, Comp...)
Affinity DataKi:  0.800nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710529(US20250002493, Embodiment 55 | US20250002493, Comp...)
Affinity DataKi:  1.60nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [238-358](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710529(US20250002493, Embodiment 55 | US20250002493, Comp...)
Affinity DataKi:  12.3nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent