BDBM710531 US20250002493, Compound I-3-8::US20250002493, Embodiment 57

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCc2c1cc(Cc1ccc(F)cc1F)c(=O)n2CC(F)(F)F)C(C)(C)C

InChI Key InChIKey=FLOFERYEJWPXFA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 710531   

TargetBaculoviral IAP repeat-containing protein 2 [254-364](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710531(US20250002493, Embodiment 57 | US20250002493, Comp...)
Affinity DataKi:  1.30nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetBaculoviral IAP repeat-containing protein 3 [236-342](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710531(US20250002493, Embodiment 57 | US20250002493, Comp...)
Affinity DataKi:  2.10nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase XIAP [238-358](Human)
Nanjing China-Australia Institute of Translational Medicine

US Patent
LigandPNGBDBM710531(US20250002493, Embodiment 57 | US20250002493, Comp...)
Affinity DataKi:  7.10nMAssay Description:The binding affinity of the compounds provided by the present invention to IAP proteins was determined using a fluorescence polarization method (Niko...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/15/2025
Entry Details
Go to US Patent