BDBM712502 US12194050, Example 12

SMILES COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)Nc3cccc(C(F)(F)F)c3)=C2)cc1OC

InChI Key InChIKey=PWKDRVWDINBPGS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 712502   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Richter Gedeon

US Patent
LigandPNGBDBM712502(US12194050, Example 12)
Affinity DataEC50:  230nMAssay Description:α7 cells cells stably expressing human α7 nAchR were cultured in the medium detailed above, and were split twice a week. For the fluorometric measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent