BDBM712821 US20250019369, Example 20

SMILES O=C(N[C@H]1CC[C@H](NCC(F)(F)F)CC1)c1cc(C2CC2)cc(-n2ccnc2)n1

InChI Key InChIKey=JDJJDVGHDWZGFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712821   

LigandPNGBDBM712821(US20250019369, Example 20)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit human CD38 hydrolase activity was measured in a fluorescence-based assay using non-physiological NAD+ substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent

LigandPNGBDBM712821(US20250019369, Example 20)
Affinity DataIC50: 40nMAssay Description:The ability of test compounds to inhibit mouse CD38 hydrolase activity was measured in a fluorescence-based assay using non-physiological NAD+ substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent