BDBM715900 6-Amino-3-((1R,3S)-4'-chloro-3-(4-ethyl-1H- pyrazol-1-yl)-1',2'-dihydrospiro[cyclopentane-1,3'- pyrrolo[2,3-b]pyridin]-5'-yl)-2-fluoro-N,N- dimethylbenzamide 6-Amino-3-((1S,3R)-4'-chloro-3-(4-ethyl-1H- pyrazol-1-yl)-1',2'-dihydrospiro[cyclopentane-1,3'- pyrrolo[2,3-b]pyridin]-5'-yl)-2-fluoro-N,N- dimethylbenzamide::US12208088, Compound 170a

SMILES CCc1cnn(C2CCC3(CNc4ncc(-c5ccc(N)c(C(=O)N(C)C)c5F)c(Cl)c43)C2)c1

InChI Key InChIKey=PGMSRQUFXGPARV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715900   

LigandPNGBDBM715900(6-Amino-3-((1R,3S)-4'-chloro-3-(4-ethyl-1H- pyrazo...)
Affinity DataKi:  5.54nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
6/3/2025
Entry Details
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