BDBM715985 (R)-(6-Amino-3-(4'-chloro-1',2'- dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-3-en-5'-yl)-2-fluorophenyl)(2-(1- methyl-1H-pyrazol-4-yl)piperidin-1-yl)methanone (S)-(6-Amino-3-(4'-chloro-1',2'- dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-3-en-5'-yl)-2-fluorophenyl)(2-(1- methyl-1H-pyrazol-4-yl)piperidin-1-yl)methanone::US12208088, Compound 239a

SMILES Cn1cc([C@H]2CCCCN2C(=O)c2c(N)ccc(-c3cnc4c(c3Cl)C3(CC=CC3)CN4)c2F)cn1

InChI Key InChIKey=CTMGGBZIJICOCR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 715985   

LigandPNGBDBM715985((R)-(6-Amino-3-(4'-chloro-1',2'- dihydrospiro[cycl...)
Affinity DataKi:  0.890nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent