BDBM716006 2-(2-(3-(1',2'-Dihydrospiro[cyclopropane-1,3'- pyrrolo[2,3-b]pyridin]-5'-yl)-2-fluorophenyl)-3- methylpyridin-4-yl)acetonitrile::US12208088, Compound 251

SMILES Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2)C2(CC2)CN3)c1F

InChI Key InChIKey=YJDLAVNXGVSRFT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716006   

LigandPNGBDBM716006(2-(2-(3-(1',2'-Dihydrospiro[cyclopropane-1,3'- pyr...)
Affinity DataKi:  3.15nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent