BDBM716007 2-(2-(3-(4'-Chloro-1',2'- dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3- b]pyridin]-3-en-5'-yl)-2-fluorophenyl)-3- methylpyridin-4-yl)acetonitrile::US12208088, Compound 252

SMILES Cc1c(CC#N)ccnc1-c1cccc(-c2cnc3c(c2Cl)C2(CC=CC2)CN3)c1F

InChI Key InChIKey=NZICGVPZWATWMC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716007   

LigandPNGBDBM716007(2-(2-(3-(4'-Chloro-1',2'- dihydrospiro[cyclopentan...)
Affinity DataKi:  5.94nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/3/2025
Entry Details
Go to US Patent