BDBM716409 US20250034108, Example 57

SMILES C[C@@](O)(CS(N)(=O)=O)c1cccc(-c2nc(Cc3cc(OC(F)(F)F)ccc3F)no2)n1

InChI Key InChIKey=AQGOCHNZBJKTPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 716409   

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandPNGBDBM716409(US20250034108, Example 57)
Affinity DataIC50: 3.60E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandPNGBDBM716409(US20250034108, Example 57)
Affinity DataIC50: 2.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent