BDBM716417 US20250034108, Example 63

SMILES Cc1ccc(F)c(Cn2nnc(-c3cccc([C@@](C)(O)CS(N)(=O)=O)n3)n2)c1Cl

InChI Key InChIKey=UVOLPSCNNPEDPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716417   

TargetSodium channel protein type 5 subunit alpha(Human)
Novartis

US Patent
LigandPNGBDBM716417(US20250034108, Example 63)
Affinity DataIC50: 3.80E+3nMAssay Description:To assess peak Nav1.5 current inhibition in an atrial fibrillation-mimicking condition (Nav1.5 IC50 (5 Hz, AF-like rate) (μM)), compounds were first ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
Go to US Patent