BDBM717048 2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((1S,6S)-5-(5-hydroxy- 6-methylpyrimidine-4-carbonyl)-2,5-diazabicyclo[4.2.0]octan-2-yl)-8- oxopyrido[2,3-b]pyrazin-5(8H)-yl)-N-(2-chloro-4- (trifluoromethyl)phenyl)acetamide (single stereoisomer, second eluting compound as stereoisomer 2, cis)::US20250034136, Compound I-220

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)[C@H]3CC[C@@H]32)c(=O)c2nc(N3CC[C@@H]4C[C@@H]43)cnc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key InChIKey=MZJGFRHLSJTOOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 717048   

LigandPNGBDBM717048(2-(2-(2-azabicyclo[3.1.0]hexan-2-yl)-6-ethyl-7-((1...)
Affinity DataIC50: 5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
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