BDBM717906 US20250042857, Example A-40

SMILES COc1cc2nccc(N[C@H](C)c3cccc(C(F)F)c3F)c2cc1C1CCN(C(C)=O)CC1

InChI Key InChIKey=WBEQVQFNLGSLAA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 717906   

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Haihe Biopharma Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM717906(US20250042857, Example A-40)
Affinity DataIC50: 11nMAssay Description:Inhibition of SOS1/KRAS G12C mutant (unknown origin) protein-protein interaction incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Haihe Biopharma Co.

US Patent
LigandPNGBDBM717906(US20250042857, Example A-40)
Affinity DataIC50: 100nMAssay Description:Experimental reagents: KRASG12C/SOS binding kit (Cisbio, cat. 63ADK000CB16PEG); DMSO (Sigma, cat. D8418-1L); and 384-well white plate (PerkinElmer, c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
US Patent