BDBM719121 US20250049809, Example 7

SMILES C=CC(=O)N1CCN(C2CCCCCCN3C(=O)OCc4cnc(nc43)N[C@@H](C)c3ccc2cc3)CC1

InChI Key InChIKey=OYEBZVOYEZNVOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719121   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H,S280F](Human)
University Of Texas

US Patent
LigandPNGBDBM719121(US20250049809, Example 7)
Affinity DataIC50: 295nMAssay Description:The enzymatic activity of mIDH1R132H/S280F was assessed by measuring the fluorescence of the NADPH. The assay was performed in 384 well, white ProxiP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent

TargetIsocitrate dehydrogenase [NADP], mitochondrial [R140Q](Human)
University Of Texas

US Patent
LigandPNGBDBM719121(US20250049809, Example 7)
Affinity DataIC50: 1.73E+3nMAssay Description:The enzymatic activity of mIDH2R140Q was assessed by measuring the fluorescence of the NADPH. The assay was performed in 384 well, white ProxiPlates ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
Go to US Patent