BDBM72039 3,5-bis(difluoromethyl)-1-{[2-(3,4-dimethylphenyl)-4-quinolinyl]carbonyl}-4,5-dihydro-1H-pyrazol-5-ol::MLS000545506::SMR000160266::[3,5-bis(difluoromethyl)-5-hydroxy-2-pyrazolin-1-yl]-[2-(3,4-dimethylphenyl)-4-quinolyl]methanone::[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(3,4-dimethylphenyl)-4-quinolinyl]methanone::[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(3,4-dimethylphenyl)quinolin-4-yl]methanone::[3,5-bis[bis(fluoranyl)methyl]-5-oxidanyl-4H-pyrazol-1-yl]-[2-(3,4-dimethylphenyl)quinolin-4-yl]methanone::cid_4154942

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(CN5CCO[C@](C)(CCN)C5)cn4)ncc3F)cc2n1C(C)C

InChI Key InChIKey=SNYVAIVACJFSEV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72039   

TargetCyclin-dependent kinase 6(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72039BDBM72039(US12486280, Compound A21)
Affinity DataKi:  730nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72039BDBM72039(US12486280, Compound A21)
Affinity DataKi:  4.90E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details
US Patent