BDBM72051 5-[2-[(E)-(3-methoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile::5-[2-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-3-methylsulfanyl-1,2-thiazole-4-carbonitrile::5-[N'-[(E)-(4-keto-3-methoxy-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-3-(methylthio)isothiazole-4-carbonitrile::5-[[(E)-(3-methoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-3-(methylthio)-4-isothiazolecarbonitrile::MLS000521543::SMR000131951::cid_6323625

SMILES COc1cc(CN=Nc2snc(SC)c2C#N)ccc1O

InChI Key InChIKey=GKLKMZWTLNXCKR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72051   

TargetCyclin-dependent kinase 6(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72051BDBM72051(US12486280, Compound A55)
Affinity DataKi:  1.60E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72051BDBM72051(US12486280, Compound A55)
Affinity DataKi:  1.19E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details US Patent

TargetCyclin-dependent kinase 4(Human)
California Institute Of Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 72051BDBM72051(US12486280, Compound A55)
Affinity DataIC50: 2.60E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2026
Entry Details US Patent