BDBM72073 MLS000545991::N-[3-cyano-1-(2-furanylmethyl)-4,5-diphenyl-2-pyrrolyl]-2-thiophenecarboxamide::N-[3-cyano-1-(2-furfuryl)-4,5-diphenyl-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(2-furylmethyl)-4,5-diphenyl-1H-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(furan-2-ylmethyl)-4,5-diphenyl-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(furan-2-ylmethyl)-4,5-diphenylpyrrol-2-yl]thiophene-2-carboxamide::SMR000162939::cid_1050694

SMILES O=C(Nc1c(C#N)c(c(-c2ccccc2)n1Cc1ccco1)-c1ccccc1)c1cccs1

InChI Key InChIKey=CTZROLIJCRVSTP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72073   

TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM72073(N-[3-cyano-1-(2-furylmethyl)-4,5-diphenyl-1H-pyrro...)
Affinity DataIC50: 6.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM72073(N-[3-cyano-1-(2-furylmethyl)-4,5-diphenyl-1H-pyrro...)
Affinity DataIC50: 6.95E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Torrey Pines Institute for Molecul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM72073(N-[3-cyano-1-(2-furylmethyl)-4,5-diphenyl-1H-pyrro...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay