BDBM72180 2-(N-besyl-2,3-dimethyl-anilino)-N-(2-phenylphenyl)acetamide::2-[(2,3-dimethylphenyl)-(phenylsulfonyl)amino]-N-(2-phenylphenyl)ethanamide::2-[N-(benzenesulfonyl)-2,3-dimethylanilino]-N-(2-phenylphenyl)acetamide::MLS000578975::N~1~-2-biphenylyl-N~2~-(2,3-dimethylphenyl)-N~2~-(phenylsulfonyl)glycinamide::SMR000198689::cid_1316829

SMILES C[C@@H](NC(=O)c1cc(N2CCOCC2)c(F)cc1N[C@H]1CN2CCC1CC2)C1=C(F)C(C(F)F)CC=C1

InChI Key InChIKey=MNLATDJRCMOWDC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72180   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72180BDBM72180(N-((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)...)
Affinity DataIC50: 12.9nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent