BDBM72183 2-[3-(2,5-dimethylphenoxy)-4-keto-chromen-7-yl]oxy-N-(2-ethylphenyl)acetamide::2-[3-(2,5-dimethylphenoxy)-4-oxidanylidene-chromen-7-yl]oxy-N-(2-ethylphenyl)ethanamide::2-[3-(2,5-dimethylphenoxy)-4-oxochromen-7-yl]oxy-N-(2-ethylphenyl)acetamide::2-[[3-(2,5-dimethylphenoxy)-4-oxo-1-benzopyran-7-yl]oxy]-N-(2-ethylphenyl)acetamide::2-{[3-(2,5-dimethylphenoxy)-4-oxo-4H-chromen-7-yl]oxy}-N-(2-ethylphenyl)acetamide::MLS000578904::SMR000198724::cid_1193507

SMILES C[C@@H](NC(=O)c1cc(N2CCOCC2)c(F)cc1N[C@@H]1[C@@H]2C[C@H]1CN(C)C2)c1cccc(C(F)F)c1F

InChI Key InChIKey=SAAXXJNFEVIEML-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72183   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72183BDBM72183(N-((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)...)
Affinity DataIC50: 17.8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent