BDBM72225 (4-Chloro-6-isopropylamino-[1,3,5]triazin-2-yl)-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyanamide::MLS000588891::SMR000212453::[1,3-bis(oxidanylidene)isoindol-2-yl]methyl-[4-chloranyl-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]cyanamide::[4-chloro-6-(isopropylamino)-s-triazin-2-yl]-(phthalimidomethyl)cyanamide::[4-chloro-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,3-dioxo-2-isoindolyl)methyl]cyanamide::[4-chloro-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,3-dioxoisoindol-2-yl)methyl]cyanamide::cid_1929026

SMILES CC(C)Nc1nc(Cl)nc(n1)N(CN1C(=O)c2ccccc2C1=O)C#N

InChI Key InChIKey=ATWCWDRQBGNNFG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72225   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72225BDBM72225(US20250368634, Example 57)
Affinity DataIC50: 9.80nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
Target InfoKEGG
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Date in BDB:
4/15/2026
Entry Details US Patent