BDBM72228 7-(2,4-Dinitro-phenoxy)-chromen-2-one::7-(2,4-dinitrophenoxy)-1-benzopyran-2-one::7-(2,4-dinitrophenoxy)chromen-2-one::7-(2,4-dinitrophenoxy)coumarin::MLS000588020::SMR000211941::cid_1908550

SMILES C[C@@H](NC(=O)c1cc(-c2ccn(C)c(=O)c2)c(F)cc1NC1CCN(C)CC1)c1cccc(C(F)F)c1F

InChI Key InChIKey=FKGRKMCAKYMDRU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72228   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72228BDBM72228(US20250368634, Example 60)
Affinity DataIC50: 11nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent