BDBM72232 (4Z)-2-(4-butoxyphenyl)-4-[(1,3-thiazol-2-ylamino)methylene]-1,3-oxazol-5(4H)-one::(4Z)-2-(4-butoxyphenyl)-4-[(1,3-thiazol-2-ylamino)methylidene]-1,3-oxazol-5-one::(4Z)-2-(4-butoxyphenyl)-4-[(2-thiazolylamino)methylidene]-5-oxazolone::(4Z)-2-(4-butoxyphenyl)-4-[(thiazol-2-ylamino)methylene]-2-oxazolin-5-one::MLS000586532::SMR000207911::cid_6259969

SMILES C[C@@H](NC(=O)c1cc(-c2ccncc2F)c(F)cc1NC1CCN(C)CC1)c1cccc(C(F)F)c1F

InChI Key InChIKey=QSXVMWZJGVDGJR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72232   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72232BDBM72232((R)-N-(1-(3- (difluoromethyl)-2- fluorophenyl)ethy...)
Affinity DataIC50: 14.9nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent