BDBM72233 MLS000590866::N-[4-(9H-fluoren-9-yl)-1-piperazinyl]-1-(3,4,5-trimethoxyphenyl)methanimine::N-[4-(9H-fluoren-9-yl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)methanimine::SMR000217712::[4-(9H-Fluoren-9-yl)-piperazin-1-yl]-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-amine::[4-(9H-fluoren-9-yl)piperazino]-(3,4,5-trimethoxybenzylidene)amine::cid_1039261

SMILES Cc1cc(-c2cc(C(=O)N[C@H](C)c3cccc(C(F)F)c3F)c(NC3CCN(C)CC3)cc2F)ccn1

InChI Key InChIKey=PWBFJEQCGAJBMN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72233   

TargetGTPase KRas [1-169,G12C](Human)
SchroDinger

US Patent
LigandChemical structure of BindingDB Monomer ID 72233BDBM72233((R)-N-(1-(3- (difluoromethyl)-2- fluorophenyl)ethy...)
Affinity DataIC50: 8.30nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent