BDBM722520 N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)furo[3,2-c]pyridin-3-yl)-2-((4-fluorobenzyl)oxy)phenyl)-2,2,2-trifluoroethane-1-sulfonamide::US20250059188, Compound 11::US20250115598, Compound 11

SMILES Nc1ncc(-c2cnn(C3CCOCC3)c2)c2occ(-c3ccc(NS(=O)(=O)CC(F)(F)F)c(OCc4ccc(F)cc4)c3)c12

InChI Key InChIKey=HDLYPVOSYBVGHP-UHFFFAOYSA-N

Data  8 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 722520   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Mus musculus)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd:  50.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd:  275nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd: >2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd: >2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Mus musculus)
Anaxis Pharma

US Patent
LigandPNGBDBM722520(N-(4-(4-amino-7-(1-(tetrahydro-2H-pyran-4-yl)-1H-p...)
Affinity DataKd:  275nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent