BDBM722522 N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyran-4-yl)-1H- pyrazol-4-yl)- 1H-pyrazolo[4,3- c]pyridin- 3-yl)-2-((4- fluorobenzyl) oxy)phenyl)-1,1- difluoromethane- sulfonamide::US20250059188, Compound 13::US20250115598, Compound 13

SMILES Cn1nc(-c2ccc(NS(=O)(=O)C(F)F)c(OCc3ccc(F)cc3)c2)c2c(N)ncc(-c3cnn(C4CCOCC4)c3)c21

InChI Key InChIKey=NZGUQMHRVWVFHK-UHFFFAOYSA-N

Data  8 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 722522   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Mus musculus)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: >2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Affinity DataKd: >2.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent

TargetMixed lineage kinase domain-like protein(Mus musculus)
Anaxis Pharma

US Patent
LigandPNGBDBM722522(N-(4-(4-amino- 1-methyl-7-(1- (tetrahydro-2H- pyra...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent