BDBM722526 N-(4-{4-amino-1-methyl-1Hpyrazolo[4,3-c]pyridin-3-yl}-2-[(1S)-1-(4-fluorophenyl)ethoxy]phenyl)-1,1-difluoromethanesulfonamide::US20250059188, Compound 17

SMILES C[C@H](Oc3cc(c1nn(C)c2ccnc(N)c12)ccc3NS(=O)(=O)C(F)F)c4ccc(F)cc4

InChI Key InChIKey=OBBQNBDIZPNRBM-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 722526   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722526(N-(4-{4-amino-1-methyl-1Hpyrazolo[4,3-c]pyridin-3-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722526(N-(4-{4-amino-1-methyl-1Hpyrazolo[4,3-c]pyridin-3-...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM722526(N-(4-{4-amino-1-methyl-1Hpyrazolo[4,3-c]pyridin-3-...)
Affinity DataKd: >1.00E+4nMAssay Description:For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
Go to US Patent