BDBM72253 3-(4-chlorophenyl)sulfonyl-6-fluoranyl-1-[(4-methylphenyl)methyl]quinolin-4-one::3-(4-chlorophenyl)sulfonyl-6-fluoro-1-(4-methylbenzyl)-4-quinolone::3-(4-chlorophenyl)sulfonyl-6-fluoro-1-[(4-methylphenyl)methyl]-4-quinolinone::3-(4-chlorophenyl)sulfonyl-6-fluoro-1-[(4-methylphenyl)methyl]quinolin-4-one::MLS000722119::SMR000236778::cid_2137248

SMILES CCc1c[nH]c2ncc(-c3cccc(N4CCCN(CCN5CC(c6ccc7c(c6)CN(C6CCC(=O)NC6=O)C7=O)C5)C4=O)c3)c(Cl)c12

InChI Key InChIKey=AUJYKTBJTCUIDW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72253   

LigandChemical structure of BindingDB Monomer ID 72253BDBM72253(3-[5-(1-{2-[3-(3-{4-chloro-3-ethyl-1H-pyrrolo [2, ...)
Affinity DataIC50: 1.10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 72253BDBM72253(3-[5-(1-{2-[3-(3-{4-chloro-3-ethyl-1H-pyrrolo [2, ...)
Affinity DataIC50: 4.70nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

TargetAurora kinase A(Human)
BioFront

US Patent
LigandChemical structure of BindingDB Monomer ID 72253BDBM72253(3-[5-(1-{2-[3-(3-{4-chloro-3-ethyl-1H-pyrrolo [2, ...)
Affinity DataIC50: 10.1nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent