BDBM72261 MLS000335539::N-(4-chlorophenyl)-2-[4-keto-2-phenethylimino-3-(2-thenylideneamino)thiazolidin-5-yl]acetamide::N-(4-chlorophenyl)-2-[4-oxidanylidene-2-(2-phenylethylimino)-3-(thiophen-2-ylmethylideneamino)-1,3-thiazolidin-5-yl]ethanamide::N-(4-chlorophenyl)-2-[4-oxo-2-(2-phenylethylimino)-3-(thiophen-2-ylmethylideneamino)-1,3-thiazolidin-5-yl]acetamide::N-(4-chlorophenyl)-2-[4-oxo-2-(2-phenylethylimino)-3-(thiophen-2-ylmethylideneamino)-5-thiazolidinyl]acetamide::SMR000253293::cid_4302699

SMILES O=C1CCC(N2C(=O)c3cc(F)c(N4CCC(CCN5CCCN(c6cccc(-c7cnc8[nH]cc(C9CC9)c8c7Cl)c6)C5=O)CC4)cc3C2=O)C(=O)N1

InChI Key InChIKey=JIMHUICIZFHDAF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72261   

LigandChemical structure of BindingDB Monomer ID 72261BDBM72261(5-(4-(2-(3-(3-(4-chloro-3-cyclopropyl-1H-pyrrolo [...)
Affinity DataIC50: 36.5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 72261BDBM72261(5-(4-(2-(3-(3-(4-chloro-3-cyclopropyl-1H-pyrrolo [...)
Affinity DataIC50: 62.9nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

TargetAurora kinase A(Human)
BioFront

US Patent
LigandChemical structure of BindingDB Monomer ID 72261BDBM72261(5-(4-(2-(3-(3-(4-chloro-3-cyclopropyl-1H-pyrrolo [...)
Affinity DataIC50: 131nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent