BDBM72262 5-[2-(4-cyanobenzyl)oxy-5-methyl-benzoyl]-1-cyclopropyl-2-keto-nicotinonitrile::5-[2-[(4-cyanophenyl)methoxy]-5-methyl-phenyl]carbonyl-1-cyclopropyl-2-oxidanylidene-pyridine-3-carbonitrile::5-[2-[(4-cyanophenyl)methoxy]-5-methylbenzoyl]-1-cyclopropyl-2-oxopyridine-3-carbonitrile::5-[[2-[(4-cyanophenyl)methoxy]-5-methylphenyl]-oxomethyl]-1-cyclopropyl-2-oxo-3-pyridinecarbonitrile::MLS000391234::SMR000260271::cid_2439944

SMILES Cc1ccc(OCc2ccc(cc2)C#N)c(c1)C(=O)c1cc(C#N)c(=O)n(c1)C1CC1

InChI Key InChIKey=VKXADNPRVJJZHT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72262   

LigandChemical structure of BindingDB Monomer ID 72262BDBM72262(5-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3-b] ...)
Affinity DataIC50: 7.40nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 72262BDBM72262(5-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3-b] ...)
Affinity DataIC50: 30.7nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details US Patent

TargetAurora kinase A(Human)
BioFront

US Patent
LigandChemical structure of BindingDB Monomer ID 72262BDBM72262(5-(4-((3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2, 3-b] ...)
Affinity DataIC50: 34.8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details US Patent