BDBM72269 MLS000417372::N-(3-cyano-2-thienyl)-2-[4-(2-naphthylsulfonyl)piperazino]acetamide::N-(3-cyano-2-thiophenyl)-2-[4-(2-naphthalenylsulfonyl)-1-piperazinyl]acetamide::N-(3-cyanothiophen-2-yl)-2-(4-naphthalen-2-ylsulfonylpiperazin-1-yl)acetamide::N-(3-cyanothiophen-2-yl)-2-(4-naphthalen-2-ylsulfonylpiperazin-1-yl)ethanamide::SMR000242545::cid_2483113

SMILES CCc1c[nH]c2ncc(-c3cccc(N4CCCN(CCC5CCN(c6ccc(NC7CCC(=O)NC7=O)cc6F)CC5)C4=O)c3)c(Cl)c12

InChI Key InChIKey=FSWUAQZEVKOTLN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 72269   

LigandChemical structure of BindingDB Monomer ID 72269BDBM72269(3-((4-(4-(2-(3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2,...)
Affinity DataIC50: 5.5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 72269BDBM72269(3-((4-(4-(2-(3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2,...)
Affinity DataIC50: 12.3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent

TargetAurora kinase A(Human)
BioFront

US Patent
LigandChemical structure of BindingDB Monomer ID 72269BDBM72269(3-((4-(4-(2-(3-(3-(4-chloro-3-ethyl-1H-pyrrolo [2,...)
Affinity DataIC50: 40.8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent