BDBM72331 MLS000393196::N-(2-chloranyl-5-morpholin-4-ylsulfonyl-phenyl)-2-[3-(4-methylphenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-ethanamide::N-(2-chloro-5-morpholin-4-ylsulfonylphenyl)-2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide::N-(2-chloro-5-morpholinosulfonyl-phenyl)-2-[[4-keto-3-(p-tolyl)quinazolin-2-yl]thio]acetamide::N-[2-chloro-5-(4-morpholinylsulfonyl)phenyl]-2-[[3-(4-methylphenyl)-4-oxo-2-quinazolinyl]thio]acetamide::SMR000248026::cid_3260312

SMILES O=C1c2cc(F)c(Cl)cc2N2CN1c1ccc(=O)[nH]c1CCNCc1c2ccc(F)c1F

InChI Key InChIKey=LXVNDMOMBGXXGK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72331   

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandChemical structure of BindingDB Monomer ID 72331BDBM72331(3-Chloro-2,8,9-trifluoro-10,11,12,13-tetrahydro-19...)
Affinity DataIC50: 6.31nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2026
Entry Details
US Patent