BDBM72341 2-[2-(4-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-1-yl]acetic acid [2-(2,6-diethylanilino)-2-keto-ethyl] ester::2-[2-(4-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-1-yl]acetic acid [2-(2,6-diethylanilino)-2-oxoethyl] ester::MLS000707547::SMR000241648::[2-(2,6-diethylanilino)-2-oxoethyl] 2-[2-(4-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-1-yl]acetate::[2-[(2,6-diethylphenyl)amino]-2-oxidanylidene-ethyl] 2-[2-(4-fluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinolin-1-yl]ethanoate::cid_3418260

SMILES CCc1cccc(CC)c1NC(=O)COC(=O)CC1N(CCc2ccccc12)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=BPSMFQOEMGTZFH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72341   

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandChemical structure of BindingDB Monomer ID 72341BDBM72341(2-Chloro-8-fluoro-3-(trifluoromethyl)-10,11,12,13-...)
Affinity DataIC50: 15.8nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2026
Entry Details PCBioAssay