BDBM72367 5-(phenylmethyl)-3H-1,3-thiazole-2-thione::5-(phenylmethyl)-3H-thiazole-2-thione::5-benzyl-1,3-thiazole-2(3H)-thione::5-benzyl-3H-1,3-thiazole-2-thione::5-benzyl-4-thiazoline-2-thione::MLS000703077::SMR000224581::cid_824442

SMILES N#Cc1c(F)ccc2c1CNCCc1[nH]c(=O)ccc1N1CN2c2cc(C(F)(F)F)c(F)cc2C1=O

InChI Key InChIKey=AFVOLGCBZDOUOP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72367   

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandChemical structure of BindingDB Monomer ID 72367BDBM72367(Step A: 2,8-Difluoro-15,19-dioxo-3-(trifluoromethy...)
Affinity DataIC50: 12.6nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2026
Entry Details
US Patent