BDBM72372 (E)-3-(3-methoxy-4-phenylmethoxy-phenyl)-1-morpholin-4-yl-prop-2-en-1-one::(E)-3-(3-methoxy-4-phenylmethoxyphenyl)-1-(4-morpholinyl)-2-propen-1-one::(E)-3-(3-methoxy-4-phenylmethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one::(E)-3-(4-benzoxy-3-methoxy-phenyl)-1-morpholino-prop-2-en-1-one::4-{3-[4-(benzyloxy)-3-methoxyphenyl]acryloyl}morpholine::MLS000677061::SMR000270883::cid_1188931

SMILES COc1cc(\C=C\C(=O)N2CCOCC2)ccc1OCc1ccccc1

InChI Key InChIKey=LTMHFUNKWUPIMP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72372   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM72372((E)-3-(3-methoxy-4-phenylmethoxyphenyl)-1-morpholi...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetAmyloid-beta precursor protein(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM72372((E)-3-(3-methoxy-4-phenylmethoxyphenyl)-1-morpholi...)
Affinity DataIC50: 7.81E+4nMAssay Description:Inhibition of human biotinylated amyloid beta (1 to 42) oligomerization assessed as decrease in oligomer abundance measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed