BDBM723861 US20250064789, Compound 440

SMILES O=C(CNC(=O)c1ccc(Cl)c(Cl)c1)N[C@H](Cc2ccccc2)C(=O)C(=O)NCc3ccccn3

InChI Key InChIKey=VWUQBNXKBUKZRM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 723861   

TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM723861(US20250064789, Compound 440)
Affinity DataIC50: 20nMAssay Description:Inhibition of SARS-CoV-2 main protease by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetReplicase polyprotein 1a(2019-nCoV)
Westvac Biopharma Co.

US Patent
LigandPNGBDBM723861(US20250064789, Compound 440)
Affinity DataIC50: 2.04E+4nMAssay Description:The recombinant SARS-CoV-2 Mpro (with a final concentration of 750 nM) was mixed with a series of dilutions for each compound in 25 μL assay buffer (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/29/2025
Entry Details
US Patent