BDBM724678 1-(2-chlorophenyl)-N- ((1r,4r)-4-(3-(difluoro- methoxy)azetidin-1-yl)- cyclohexyl)-3-methyl- 1H-thieno[2,3-c]pyr- azole-5-carboxamide::US20250066383, Compound I-7

SMILES Cc1nn(-c2ccccc2Cl)c2sc(C(=O)N[C@H]3CC[C@H](N4CC(OC(F)F)C4)CC3)cc12

InChI Key InChIKey=NOXHXLSJGGLIAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724678   

LigandPNGBDBM724678(1-(2-chlorophenyl)-N- ((1r,4r)-4-(3-(difluoro- met...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724678(1-(2-chlorophenyl)-N- ((1r,4r)-4-(3-(difluoro- met...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent