BDBM724698 N-((1r,4r)-4-(4- (dimethylcarbamo- yl)piperazin-1-yl)- cyclohexyl)-1-iso- butyl-3-methyl-1H- thieno[2,3-c]pyrazole- 5-carboxamide::US20250066383, Compound II-19

SMILES Cc1nn(CC(C)C)c2sc(C(=O)N[C@H]3CC[C@H](N4CCN(C(=O)N(C)C)CC4)CC3)cc12

InChI Key InChIKey=KYOVBYNCDPCDGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724698   

LigandPNGBDBM724698(N-((1r,4r)-4-(4- (dimethylcarbamo- yl)piperazin-1-...)
Affinity DataIC50: 20nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
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LigandPNGBDBM724698(N-((1r,4r)-4-(4- (dimethylcarbamo- yl)piperazin-1-...)
Affinity DataIC50: 65nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent