BDBM724706 N-((1r,4r)-4-(3,3- difluoropyrrolidin-1- yl)cyclohexyl)-3- methyl-1-neopentyl- 1H-thieno[2,3-c]pyr- azole-5-carboxamide::US20250066383, Compound II-27

SMILES Cc1nn(CC(C)(C)C)c2sc(C(=O)N[C@H]3CC[C@H](N4CCC(F)(F)C4)CC3)cc12

InChI Key InChIKey=NJARYVQLYUOQMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 724706   

LigandPNGBDBM724706(N-((1r,4r)-4-(3,3- difluoropyrrolidin-1- yl)cycloh...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent

LigandPNGBDBM724706(N-((1r,4r)-4-(3,3- difluoropyrrolidin-1- yl)cycloh...)
Affinity DataIC50: 10nMAssay Description:Compounds were tested for their activity by measuring the inhibition of PDE7A or PDE7B hydrolysis of [3H]cAMP to [3H]AMP. Generally, eight dilutions ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/30/2025
Entry Details
Go to US Patent