BDBM7249 (3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]pyrrol-1-yl}methylidene)-2,3-dihydro-1H-indol-2-one::pyrrollylactone indolinone driv. 15k

SMILES OCCc1cccc2NC(=O)\C(=C/c3[nH]cc4c3CCOC4=O)c12

InChI Key InChIKey=KJUURYWTEJSJCF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7249   

LigandPNGBDBM7249((3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyra...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2006
Entry Details Article
PubMed
LigandPNGBDBM7249((3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyra...)
Affinity DataIC50: 1.20E+3nMT: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2006
Entry Details Article
PubMed
LigandPNGBDBM7249((3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyra...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2006
Entry Details Article
PubMed
LigandPNGBDBM7249((3Z)-4-(2-hydroxyethyl)-3-({4-oxo-2H,4H,6H,7H-pyra...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:For the assay, purified cdk/cyclin was added to polystyrene 96-well plates that were precoated with GST-Rb substrate in the presence of ATP. After i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2006
Entry Details Article
PubMed