BDBM72496 1-(2-furfuryl)-1-[(2-keto-5,7-dimethyl-1H-quinolin-3-yl)methyl]-3-(tetrahydrofurfuryl)thiourea::1-[(5,7-dimethyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]-1-(furan-2-ylmethyl)-3-(oxolan-2-ylmethyl)thiourea::1-[(5,7-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(2-furanylmethyl)-3-(2-oxolanylmethyl)thiourea::1-[(5,7-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-(furan-2-ylmethyl)-3-(oxolan-2-ylmethyl)thiourea::MLS000856523::SMR000274880::cid_3169921

SMILES CCn1cc(C(F)(F)F)nc1-c1ccc(Cn2c3cc(C#N)ccc3c3cnc(-c4c(OC)ncnc4C4CC4)nc32)cc1

InChI Key InChIKey=JUWVFMBLRZYEBS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72496   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandChemical structure of BindingDB Monomer ID 72496BDBM72496(US20250368667, Compound 50)
Affinity DataIC50: 4.84nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent