BDBM72584 (4-benzylpiperazin-1-yl)((2S,4R)-4-cyclopropyl-2-(4-(hydroxymethyl)benzyloxy)-3,4-dihydro-2H-pyran-6-yl)methanone::(4-benzylpiperazin-1-yl)-[(2S,4R)-4-cyclopropyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-yl]methanone::(4-benzylpiperazino)-[(2S,4R)-4-cyclopropyl-2-(4-methylolbenzyl)oxy-3,4-dihydro-2H-pyran-6-yl]methanone::MLS000766463::SMR000389579::[(2S,4R)-4-cyclopropyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-yl]-[4-(phenylmethyl)-1-piperazinyl]methanone::[(2S,4R)-4-cyclopropyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-yl]-[4-(phenylmethyl)piperazin-1-yl]methanone::cid_16195827

SMILES COc1ncnc(C2CC2)c1-c1ncc2c3ccc(N4CC(OC)C4)nc3n(Cc3ccc4c(c3)CCCn3cc(C(F)(F)F)nc3-4)c2n1

InChI Key InChIKey=FRNLWWDSDTWVDL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72584   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Shanghai Qilu Pharmaceutical Research and Development Centre

US Patent
LigandChemical structure of BindingDB Monomer ID 72584BDBM72584(US20250368667, Compound 137)
Affinity DataIC50: 1.54nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2026
Entry Details
US Patent