BDBM726287 US12247004, Compound ANASIA-118

SMILES CC(C)[C@H](N)C(=O)N=[S@@](N)(=O)c1cccc(OC(F)F)c1

InChI Key InChIKey=RWVNAYRJJQKWRP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 726287   

TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
Oxford Drug Design

US Patent
LigandPNGBDBM726287(US12247004, Compound ANASIA-118)
Affinity DataIC50: 5.29E+4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent

TargetValine--tRNA ligase()
Oxford Drug Design

US Patent
LigandPNGBDBM726287(US12247004, Compound ANASIA-118)
Affinity DataIC50: 3.86E+4nMAssay Description:Leucyl-tRNA Synthetasea. Single Point Percentage InhibitionThe activity of the pathogenic aaRSs was monitored by measuring AMP production using the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/14/2025
Entry Details
Go to US Patent