BDBM7315 8,18-di-tert-butyl 14-bromo-9-oxo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaene-8,18-dicarboxylate::9-bromo-5,12-bis-(tert-butyloxycarbonyl)-paullone::CHEMBL317562::NSC 702374::Paullone Analog 54

SMILES CC(C)(C)OC(=O)N1c2ccccc2-c2c(CC1=O)c1cc(Br)ccc1n2C(=O)OC(C)(C)C

InChI Key InChIKey=MRTWJQDNVKEBIF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7315   

LigandPNGBDBM7315(8,18-di-tert-butyl 14-bromo-9-oxo-8,18-diazatetrac...)
Affinity DataIC50: 6.40E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7315(8,18-di-tert-butyl 14-bromo-9-oxo-8,18-diazatetrac...)
Affinity DataIC50: 1.00E+6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7315(8,18-di-tert-butyl 14-bromo-9-oxo-8,18-diazatetrac...)
Affinity DataIC50: 1.00E+6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM7315(8,18-di-tert-butyl 14-bromo-9-oxo-8,18-diazatetrac...)
Affinity DataIC50: 1.00E+6nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed