BDBM733710 US20250127913, Compound I-79

SMILES N#Cc1ccc(F)c([C@@H](C)Nc2c(Cl)c(C)nc3cc(F)c(-c4cnc(N5CCN(C(=O)COCCOCCOCCOCCOCCOCCn6cc(CC[C@H](NC(=O)c7ccc(SCc8ccc9nc(N)nc(O)c9c8)cc7)C(=O)O)nn6)CC5)nc4)nc23)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 733710   

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733710(US20250127913, Compound I-79)
Affinity DataIC50: 3.20nMAssay Description:Table 15: Folate receptor binding was measured in black 96-well plates using a fluorescence polarization assay. A fluorescent probe consisting of a f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733710(US20250127913, Compound I-79)
Affinity DataIC50: 17nMAssay Description:Table 15: TNFα binding was measured in black 96-well plates using a time-resolved FRET assay using a previously described fluorescence acceptor TNFα ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent