BDBM733972 US20250127913, Compound I-86

SMILES Cc1nc2cc(F)c(-c3cnc(N4CCN(C(=O)COCCOCCOCCOCCOCCOCCn5cc(CC[C@H](NC(=O)c6ccc(N(C)Cc7cnc8nc(N)[nH]c(=O)c8n7)cc6)C(=O)O)nn5)CC4)nc3)nc2c(N[C@H](C)c2cc(C#N)ccc2F)c1Cl

InChI Key

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 733972   

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733972(US20250127913, Compound I-86)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733972(US20250127913, Compound I-86)
Affinity DataIC50: 7.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733972(US20250127913, Compound I-86)
Affinity DataKd:  0.0230nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent