BDBM733999 US20250127913, Compound I-90

SMILES Cc1nc2cc(F)c(-c3cnc(N4CCN(C(=O)COCCn5cc(CCCN6CCC7(CC6)CCN(C(=O)CC[C@H](NC(=O)c6ccc(NCc8cnc9nc(N)nc(O)c9n8)cc6)C(=O)O)CC7)nn5)CC4)nc3)nc2c(N[C@H](C)c2cc(C#N)ccc2F)c1Cl

InChI Key

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 733999   

TargetTumor necrosis factor(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733999(US20250127913, Compound I-90)
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733999(US20250127913, Compound I-90)
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent

TargetFolate receptor beta(Human)
Lycia Therapeutics

US Patent
LigandPNGBDBM733999(US20250127913, Compound I-90)
Affinity DataKd:  0.00500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
Go to US Patent