BDBM7351 6-(4-Chlorophenyl)[5H]pyrrolo[2,3-b]pyrazine::6-(4-chlorophenyl)-5H-pyrrolo[2,3-b]pyrazine::6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 19

SMILES Clc1ccc(cc1)-c1cc2nccnc2[nH]1

InChI Key InChIKey=VFKHBJJSGUYSDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7351   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7351(6-(4-Chlorophenyl)[5H]pyrrolo[2,3-b]pyrazine | 6-(...)
Affinity DataIC50: 1.80E+3nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed