BDBM736194 (4S,4'S)-6-chloro-4,-[(ethylamino)methyl]-1,-(4-isoquinolyl)-2-[(3-methylisoxazol-5-yl)methyl]spiro[3H-isoquinoUne-4,3'-pyrrolidine]-1,2,-dione::WO2025125695, Example 2

SMILES CCNC[C@H]1CN(c2cncc3ccccc23)C(=O)[C@@]12CN(Cc1cc(C)no1)C(=O)c1ccc(Cl)cc12

InChI Key

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 736194   

TargetReplicase polyprotein 1ab(2019-nCoV)
Medchemica

WIPO
LigandPNGBDBM736194((4S,4'S)-6-chloro-4,-[(ethylamino)methyl]-1,-(4-is...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/28/2025
Entry Details
WIPO WO2025125695

TargetReplicase polyprotein 1ab(SARS-CoV)
Medchemica

WIPO
LigandPNGBDBM736194((4S,4'S)-6-chloro-4,-[(ethylamino)methyl]-1,-(4-is...)
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/28/2025
Entry Details
WIPO WO2025125695

TargetTransmembrane protease serine 2(Human)
Medchemica

WIPO
LigandPNGBDBM736194((4S,4'S)-6-chloro-4,-[(ethylamino)methyl]-1,-(4-is...)
Affinity DataEC50:  10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/28/2025
Entry Details
WIPO WO2025125695

TargetAngiotensin-converting enzyme 2(Human)
Medchemica

WIPO
LigandPNGBDBM736194((4S,4'S)-6-chloro-4,-[(ethylamino)methyl]-1,-(4-is...)
Affinity DataEC50:  15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/28/2025
Entry Details
WIPO WO2025125695