BDBM7373 6-phenyl[5H]pyrrolo[2,3-b]pyrazine (aloisine) 44::7-Benzyl-6-phenyl[5H]pyrrolo[2,3-b]pyrazine::7-benzyl-6-phenyl-5H-pyrrolo[2,3-b]pyrazine

SMILES C(c1c([nH]c2nccnc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=CBALVKLWBKZXIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7373   

TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7373(7-Benzyl-6-phenyl[5H]pyrrolo[2,3-b]pyrazine | 7-be...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7373(7-Benzyl-6-phenyl[5H]pyrrolo[2,3-b]pyrazine | 7-be...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7373(7-Benzyl-6-phenyl[5H]pyrrolo[2,3-b]pyrazine | 7-be...)
Affinity DataIC50: 2.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM7373(7-Benzyl-6-phenyl[5H]pyrrolo[2,3-b]pyrazine | 7-be...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against Glycogen synthase kinase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed